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Adult acute lymphoblastic leukemia (ALL) treatment options include chemotherapy, radiation therapy, stem cell transplant, and targeted therapy. Get detailed information about the molecular genetics, prognosis, and treatment of ALL in this summary for clinicians.

Hereditary colorectal cancer syndromes include Lynch syndrome and several polyposis syndromes (familial adenomatous polyposis, MUTYH-associated polyposis, juvenile polyposis syndrome, Peutz-Jeghers syndrome, and serrated polyposis syndrome). Learn about the genetics, clinical manifestations, management, and psychosocial aspects of these and other hereditary colon cancer syndromes in this expert-reviewed summary.

Childhood extracranial germ cell tumors treatment options include surgery, observation, and chemotherapy. Learn more about newly diagnosed and recurrent extracranial germ cell tumors in this expert-reviewed summary.

Chronic lymphocytic leukemia (CLL) treatment options can include observation, steroids, chemotherapy, targeted therapy, and/or stem cell transplant. Get detailed information about newly diagnosed and recurrent CLL and available treatment modalities in this summary for clinicians.

Genetics of Breast and Gynecologic Cancers includes information on BRCA1 and BRCA2 variants (breast and ovarian cancer) and Lynch syndrome (endometrial cancer). Get more information about hereditary breast and gynecologic cancer syndromes in this clinician summary.

Treatment for children with extracranial germ cell tumors (GCT) may involve surgical resection followed by monitoring or chemotherapy before or after surgery. Get detailed treatment information for newly diagnosed and recurrent extracranial GCTs in this summary for clinicians.

Prostate cancer prevention approaches include avoiding risk factors when possible, increasing protective factors, and chemoprevention. Learn more about prostate cancer prevention in this expert-reviewed summary.

Neuroblastoma screening does reduce the chance of dying from the disease. Not all screening tests are helpful and most have risks. Learn more about neuroblastoma and the potential benefits and harms of screening in this expert-reviewed summary.

Retinoblastoma treatment is tailored and uses treatment options including enucleation, local treatments, chemotherapy, and radiation therapy. Get detailed treatment information for newly diagnosed and recurrent retinoblastoma in this summary for clinicians.

Cancer pain can be caused by cancer itself or its treatment and can be controlled or lessened in most patients. Learn how a personal pain plan can be used to control pain in this expert-reviewed information summary.

In childhood ependymoma, cancer forms in the tissues of the brain and spinal cord. The cause of ependymoma is unknown. Find out about the molecular and clinical features, diagnosis, prognosis, treatment, and clinical trials for pediatric ependymoma, subependymoma, myxopapillary ependymoma, anaplastic ependymoma, and RELA fusion–positive ependymoma.

Ewing sarcoma treatment options include multidrug chemotherapy, surgery, and radiation therapy. Treatment approaches titrate therapeutic aggressiveness to maximizing local control while minimizing morbidity. Get detailed treatment information for Ewing sarcoma in this summary for clinicians.

Liver (hepatocellular) cancer screening, even in high risk individuals, has not been shown to be beneficial. Get detailed information about liver cancer screening, potential screening modalities, and research directions in this summary for clinicians.

Oral cavity, pharyngeal, and laryngeal cancer prevention strategies include avoiding or reducing exposure to risk factors like tobacco, alcohol, and HPV. Get detailed information about prevention of these cancers in this summary for clinicians.

Treatment options for children with liver cancer include surgery, chemotherapy, radiation, and transarterial chemoembolization or radioembolization. Get detailed information about newly diagnosed and recurrent childhood liver cancer treatment in this summary for clinicians.