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Note to Reviewers: These documents are provided as general reviewer orientation to NIH peer review. For meeting specific information, please rely on the documents and links provided by your SRO.

If you have been diagnosed with sarcoidosis, it is important that you continue your medicine, follow up with your doctor when directed, make healthy lifestyle changes, and prevent complications. Some people may achieve total, or life-long, remission. Other people may achieve temporary remission and go on to experience a relapse, or return of the disease. If you are pregnant, talk to your doctor about the medicines you take to avoid problems for you and your baby.

The goal of treatment is remission, a state in which the condition is not causing problems. Not everyone who is diagnosed with sarcoidosis needs treatment. Medicines used to treat sarcoidosis help reduce inflammation or suppress the immune system. Many people recover with few or no long-term problems.

Your doctor will diagnose sarcoidosis based on your symptoms, a physical exam, imaging tests, or a biopsy of an affected organ. The doctor will also do tests to rule out other diseases that have similar signs and symptoms.

Many people who have sarcoidosis have no signs or symptoms. Some people experience general signs and symptoms of sarcoidosis such as fatigue, fever, and weight loss. If inflammation continues, some people may develop permanent scarring, which can lead to life-threatening serious heart or lung complications.

Sarcoidosis is a condition in which immune cells form lumps, called granulomas, in your organs. Inflammation is thought to cause granulomas to form and may also lead to temporary or permanent scarring at the site of the granulomas.

Treatment for iron-deficiency anemia will depend on its cause and severity. Treatments may include iron supplements, red blood cell transfusions, changes in your eating pattern, or procedures like endoscopy to stop bleeding.

To diagnose iron-deficiency anemia, your doctor may do a physical exam, or order blood tests or other diagnostic tests. Blood tests will show a low hemoglobin level and low level of iron in your blood.

Iron-deficiency anemia can range from mild to severe. People with mild or moderate iron-deficiency anemia may not have any signs or symptoms. Common signs and symptoms of iron-deficiency anemia include pale skin, fatigue and shortness of breath. Complications of iron-deficiency anemia include heart problems such as arrhythmias and depression.

To screen for iron-deficiency anemia your doctor may order a blood test called a complete blood count (CBC). Prevention of iron-deficiency anemia includes consuming enough iron and controlling other medical conditions that are risk factors for iron-deficiency anemia.