Engineered ECM Platforms to Analyze Progression in High Grade Serous Ovarian Cancer
While standard biological methods such as two-dimensional, in vitro cell culture and in vivo animal models are useful to examine certain biological questions, the complexity of cancer requires a continuum of model systems. This collaborative study will create a foundation for tumor tissue engineering by employing multiple innovative methodologies to first characterize and then build biomimetic models of the extracellular matrix (ECM) in the tumor microenvironment. The ECM is a key element in biomimicry, and particularly important to consider in the context of cancer, where the composition and architecture of the ECM change drastically with disease progression.
Media Type: Html
- SourceUrl: https://www.cancer.gov/publishedcontent/syndication/1127270.htm
- Syndication ID: 18271
- Language: English
- Source: National Cancer Institute (NCI)
- Date Syndication Captured: Wednesday, October 31, 2018 at 06:12 PM
- Date Syndication Updated: Wednesday, October 31, 2018 at 06:12 PM
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