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Media tagged with "recruitment"

NIEHS

Innate Immunity Signal Transduction in Human Leukocytes health  research  science  environment  north carolina  clinical  study  patient  human leukocytes  innate immunity signal transduction  volunteer  clinical study  recruitment  open study  Durham  Raleigh  RTP 

The Innate Immunity Signal Transduction in Human Leukocytes is a research study to determine the response of immune cells from the bloodstream.

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NIEHS

Environmental Risk Factors for the Development of Myositis in Military Personnel health  research  science  environment  maryland  clinical  study  DC  patient  bethesda  myositis  environmental risk factors  military  volunteer  clinical study  recruitment  open study 

This study attempts to determine if environmental and geographic exposures may be related to the development of myositis during military service and to obtain an initial understanding of the possible mechanisms involved.

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NIEHS

Bisphenol A (BPA) Pharmacokinetic (PK): Controlled Exposure Study chemicals  health  research  science  environment  north carolina  clinical  study  exposure  receipt  patient  bisphenol a  bpa  pharmacokinetic  volunteer  plastic  clinical study  recruitment  open study  Durham 

Bisphenol A (BPA) is a chemical that is used primarily to make plastics, resins, and thermal paper.

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NIEHS

Blood Vessel Study health  research  science  environment  north carolina  clinical  study  patient  endothelial cells  blood vessel  volunteer  clinical study  recruitment  open study  Durham  Raleigh  RTP 

The endothelium is the inner lining of blood vessels. The cells in this lining help regulate blood flow and immune system function.

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NIEHS

Effect of Innate Immunity on the Inflammatory Response to Endotoxin health  research  science  environment  north carolina  clinical  study  inflammation  patient  immune system  innate immunity  endotoxin  volunteer  clinical study  recruitment  open study  Durham  Raleigh  RTP 

Innate immunity is the process by which white blood cells and other parts of the immune system sense and respond to potential infections by causing an inflammation.

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NIEHS

The Role of Glucocorticoid Receptor SNPs in Receptor Function and Metabolic Disease health  research  science  arthritis  diabetes  environment  north carolina  clinical  study  stress  patient  dexamethasone  metabolic disease  glucocorticoid receptor snps  volunteer  hormones  clinical study  recruitment  open study  Durham 

NIEHS researchers theorize that changes in the surface proteins of cells called receptors may predispose people to diseases, such as heart disease, arthritis, and diabetes.

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NIEHS

The Role of TGF-Beta in Asthmatic Epithelial Cell Susceptibility to RSV Infection health  research  science  asthma  environment  north carolina  clinical  study  patient  tgf-beta  rsv infection  volunteer  clinical study  recruitment  open study  Durham  Raleigh  RTP 

Asthma patients seem to be more prone to viral infections, and NIEHS scientists believe that the cells that line these patients' airways, cause this result by overproducing TGF-beta1, a protein that promotes viral growth.

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NIEHS

Studies in the Natural History & Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies health  research  science  environment  maryland  clinical  study  DC  patient  bethesda  pathogenesis of childhood-onset  adult-onset  idiopathic inflammatory myopathies  volunteer  clinical study  recruitment  open study  myopathy 

This study will evaluate subjects with adult- and childhood-onset myositis to learn more about their causes and the immune system changes and medical problems associated with them.

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NIEHS

Pathogenic Studies in Families with Twins or Siblings Discordant for Systemic Rheumatic Disorders health  research  science  environment  maryland  immune  clinical  study  DC  patient  bethesda  families with twins  systemic rheumatic disorders  pathogenic studies  rheumatic  volunteer  clinical study  recruitment  open study  autoimune 

The goal of this study is to examine the genetic and environmental risk factors in the development of autoimmune diseases in twins and same-sex siblings, when one has an autoimmune disease and the other does not.

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NIEHS

Sample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development and Testing health  research  science  environment  north carolina  clinical  study  patient  sample collection registry for quality control of biological and environmental specimens  volunteer  clinical study  recruitment  open study  Durham  Raleigh  RTP 

Researchers are interested in developing a registry protocol to obtain biologic and environmental samples anonymously from adult volunteers for use in laboratory tests and studies.

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NIEHS

Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage health  research  science  environment  north carolina  clinical  study  patient  p53  dna damage  volunteer  clinical study  recruitment  open study  Durham  Raleigh  RTP  healthy volunteer 

The gene p53 suppresses cancer and inflammation in the body, and NIEHS investigators speculate that changes in p53 lead to changes in inflammation and the ability to repair DNA damage.

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NIEHS

Environmental Risk Factors for the Anti-Synthetase Syndrome – The MYORISK Study health  research  science  environment  maryland  clinical  study  DC  patient  bethesda  anti-synthetase syndrome  myorisk study  chronic muscle weakness  volunteer  clinical study  recruitment  open study 

This study intends to investigate the genetic and environmental risk factors involved in the development of myositis, an autoimmune muscle disease that causes chronic muscle weakness.

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NIEHS

Environmental Polymorphisms Registry – DNA Registry for Diseases health  research  science  environment  north carolina  clinical  study  patient  environmental polymorphisms registry  epr  dna registry  volunteer  clinical study  recruitment  open study  Durham  Raleigh  RTP  healthy volunteer 

The Environmental Polymorphisms Registry (EPR) is a long-term initiative to collect approximately 20,000 DNA samples from individuals.

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NIEHS

Black Cohosh Study health  research  science  environment  north carolina  clinical  study  patient  anemia  herbal supplements  folate  volunteer  clinical study  recruitment  open study  Durham  Raleigh  RTP  Black Cohosh  b12 

Black Cohosh is an herbal supplement taken by some women to treat hot flashes, cramps, or other symptoms.

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