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NIEHS

Pathogenic Studies in Families with Twins or Siblings Discordant for Systemic Rheumatic Disorders

health  research  science  environment  maryland  immune  clinical  study  DC  patient  bethesda  families with twins  systemic rheumatic disorders  pathogenic studies  rheumatic  volunteer  clinical study  recruitment  open study  autoimune 

The goal of this study is to examine the genetic and environmental risk factors in the development of autoimmune diseases in twins and same-sex siblings, when one has an autoimmune disease and the other does not.

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NIEHS

Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

health  research  science  environment  north carolina  clinical  study  patient  p53  dna damage  volunteer  clinical study  recruitment  open study  Durham  Raleigh  RTP  healthy volunteer 

The gene p53 suppresses cancer and inflammation in the body, and NIEHS investigators speculate that changes in p53 lead to changes in inflammation and the ability to repair DNA damage.

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NIEHS

E-Cigs and Smoking Study

health  research  science  environment  north carolina  tobacco  clinical  smoking  study  patient  tobacco exposure  e-cigs  volunteer  e-cigarette  clinical study  recruitment  open study  Durham  Raleigh  RTP 

According to the Centers for Disease Control and Prevention, cigarette smoking causes more than 480,000 deaths each year in the United States, which translates to causing nearly one of every five deaths.

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NIEHS

Sample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development and Testing

health  research  science  environment  north carolina  clinical  study  patient  sample collection registry for quality control of biological and environmental specimens  volunteer  clinical study  recruitment  open study  Durham  Raleigh  RTP 

Researchers are interested in developing a registry protocol to obtain biologic and environmental samples anonymously from adult volunteers for use in laboratory tests and studies.

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NIEHS

Lupus

health  research  science  environment  immune system  lupus  chronic disease  autoimmune diseases 

Lupus is a chronic disease that causes the immune system to attack the body’s own tissues and organs, resulting in inflammation of the skin, joints, blood, and kidneys.

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NIEHS

The Role of Glucocorticoid Receptor SNPs in Receptor Function and Metabolic Disease

health  research  science  arthritis  diabetes  environment  north carolina  clinical  study  stress  patient  dexamethasone  metabolic disease  glucocorticoid receptor snps  volunteer  hormones  clinical study  recruitment  open study  Durham 

NIEHS researchers theorize that changes in the surface proteins of cells called receptors may predispose people to diseases, such as heart disease, arthritis, and diabetes.

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NIEHS - NIEHS

Kids-Reduce, Reuse, Recycle

health  kids  environment  reduce  healthy living  waste  recycle  CFLs  vermicomposting  reuse 

Reduce, Reuse, Recycle — Three great ways YOU can eliminate waste and protect your environment! The waste we create has to be carefully controlled to be sure that it does not harm your environment and your health.

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NIEHS

Innate Immunity Signal Transduction in Human Leukocytes

health  research  science  environment  north carolina  clinical  study  patient  human leukocytes  innate immunity signal transduction  volunteer  clinical study  recruitment  open study  Durham  Raleigh  RTP 

The Innate Immunity Signal Transduction in Human Leukocytes is a research study to determine the response of immune cells from the bloodstream.

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NIEHS

RNA Isolation from Pico-scale samples (1 cell (10-25pg) - 10mg tissue) with the PicoPure

health  research  science  environment  laboratory  protocol  rna isolation  extraction of high quality rna  picopure  animal tissue  rat liver 

Protocol for Use with CapSure™ Macro LCM Caps; Protocol for Use with <10mg Frozen Tissue

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NIEHS

Lead

lead  health  research  science  environment  michigan  cardiovascular  water  kidney  Infertility  environmental agents  lead exposure  ntp  gas  toxicology  IQ  Flint  paint  metal  nerve 

Lead is a naturally occurring metal found deep within the ground. It occurs in small amounts in ore, along with other elements such as silver, zinc or copper.

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